APOE 抗体
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北京 101111
Quick Overview for APOE 抗体 (ABIN452451)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with all isoforms E2, E3, E4 of Human Apolipoprotein E (ApoE). The antibody detects a 38 kDa band in Western Blotting.
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产品特性
- Synonyms: ApoE, Apo-E
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Human apolipoprotein E
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亚型
- IgG1
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应用备注
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ELISA. Western Blot: 1/200 with PBS, pH 7.4.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in 1 mL distilled water
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缓冲液
- PBS, pH 7.4, 0.09 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- APOE (Apolipoprotein E (APOE))
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别名
- Apolipoprotein E (Apo E)
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背景
- Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.Synonyms: Apo-E, ApoE
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基因ID
- 348
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UniProt
- P02649
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途径
- Regulation of Cell Size, Lipid Metabolism
抗原
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