Calretinin 抗体
Quick Overview for Calretinin 抗体 (ABIN452385)
抗原
See all Calretinin (CALB2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Specific for Calretinin. No cross-reaction with Calbindin and Calmodulin. The antibody is suitable for the detection of Calretinin in neurons and may be used as an aid in differential diagnosis of pleura-mesothelioma. This marker is frequently expressed in epitheloid mesothelioma, while occasionally it turns positive in sarcomatous mesothelioma and carcinoma. It was found to be negative in sarcoma (2,3) and in 90 % of adenocarcinoma.
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交叉反应 （详细）
- Species reactivity (tested):Human and Rat.
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产品特性
- Synonyms: CALB2, CAB29, 29 kDa calbindin
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免疫原
- Recombinant Human Calretinin 22kDa.
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亚型
- Ig Fraction
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anti-Calbindin 2 (CALB2) antibody
CALB2 适用: 人 WB, IHC (p), IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calbindin 2 (CALB2) (AA 28-248) antibodyCALB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calbindin 2 (CALB2) (AA 23-242) antibodyCALB2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CALB2-2602 unconjugated
anti-Calbindin 2 (CALB2) (AA 1-271) antibodyCALB2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calbindin 2 (CALB2) (AA 172-271) antibodyCALB2 适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7H1G3 unconjugated
anti-Calbindin 2 (CALB2) (AA 1-271) antibodyCALB2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1F5H1 unconjugated
anti-Calbindin 2 (CALB2) (AA 172-271) antibodyCALB2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7F12G9 unconjugated
anti-Calbindin 2 (CALB2) (AA 211-271) antibodyCALB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calbindin 2 (CALB2) antibodyMicroarray verified CALB2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB539585 unconjugated
anti-Calbindin 2 (CALB2) antibodyCALB2 适用: 豚鼠 WB, IHC, IF 宿主: 绵羊 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on Frozen and Paraffin Sections. (Improvement of staining withUnmasking Fluid G or Unmasking Fluid C)Immunoblotting. (1/40-1/50)Positive Control: Cerebral cortex, pleural mesothelioma. Incubation Time: 60 min at RT.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Stabilized Phosphate buffer, pH 7.3 containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Calretinin (CALB2) (Calbindin 2 (CALB2))
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别名
- Calretinin
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背景
- Calretinin is a 29 kDa calcium binding protein that is expressed in central and peripheral nervous system and in many normal and pathological tissues. Calretinin is also considered an important diagnostic aid in the differential diagnosis of cystic and solid ameloblastic tumors. The rat and human calretinin exhibit 98 % sequence homology and 91 % homology to many other species. Calretinin is generally expressed with two other calcium binding proteins Calbindin D-29 and parvalbumin in CNS and other peripheral tissues. Two calcium binding proteins, calbindin and calretinin, have been reported to be expressed in abundance in Purkinje cells and other cell types in the cerebellum. The antibodies against calretinin also labels the mossy fibers throughout, and climbing fibers in a distinct group of folia. They also stain several cell types in the molecular layer. There is no appreciable immunostaining of calretinin in cerebellar cortex. In the rat, antibodies against calretinin stain the Lugaro cells, and some granule cells in lobe X, they also give weak staining of all the granule cells in the other lobes. Calretinin antibodies have been used to detect a number of carcinomas by clinicopathological, immunohistochemical techniques including, epithelial malignant mesotheliomas, Ovarian yolk sac tumor, Adenomatoid tumors of the uterus etc.Synonyms: 29 kDa calbindin, CAB29, CALB2
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基因ID
- 794
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UniProt
- P22676
抗原
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