Unc5c 抗体 (Internal Region)
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Quick Overview for Unc5c 抗体 (Internal Region) (ABIN452309)
抗原
See all Unc5c 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- NCTVSEEPTG ID
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特异性
- This antibody recognizes UNC5C.
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交叉反应 (详细)
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Species reactivity (expected):Human, Canine.
Species reactivity (tested):Mouse. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence NCTVSEEPTGID, from the internal region of the protein sequence . Genename: UNC5C
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应用备注
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Peptide ELISA: 1/32000. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))
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别名
- UNC5C
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背景
- UNC5C is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It is also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. There are two named isoforms.Synonyms: Netrin receptor UNC5C, Protein unc-5 homolog C, UNC5H3, Unc-5 homolog 3
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基因ID
- 8633
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NCBI登录号
- NP_003719
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UniProt
- O95185
抗原
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