PAR1 抗体 (Internal Region)
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Quick Overview for PAR1 抗体 (Internal Region) (ABIN452298)
抗原
See all PAR1 (F2R) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody recognizes F2R/PAR1.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence C-TRARRPESKATNAT, from the Internal region (near N-terminus) of the protein sequence
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anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 251-350) antibody
F2R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 61-76), (Extracellular), (N-Term) antibodyF2R 适用: 人 WB, IHC, FACS, IF, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor (F2R) (N-Term) antibodyF2R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-102) antibodyF2R 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-176) antibodyF2R 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 5E2E6 unconjugated
anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 1-425) antibodyF2R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-102) antibodyF2R 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 130-425) antibodyF2R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 66-80), (Extracellular), (N-Term) antibodyF2R 适用: 小鼠 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor (F2R) (Internal Region) antibodyVerified F2R 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Detection limit dilution: 1/32000. Western blot: 0.5-2 μg/mL. Approx 48 kDa band observed in lysates of cell line HeLa(calculated MW of 47.8 kDa according to NP_001983.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 with 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
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别名
- Thrombin Receptor / F2R
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背景
- Thrombin receptor is a 7 transmembrane G protein coupled receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. It may play a role in platelet activation and in vascular development. Thrombin receptor expression has been documented in various blood cells, colon, kidney, liver, lung, skin, and vessel. ESTs have been isolated from adrenal, embryo, heart, heart/melanocyte/uterus, liver/spleen, pineal, skin, spleen, and vessel.Synonyms: CF2R, Coagulation factor II receptor, PAR-1, PAR1, Proteinase-activated receptor 1
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基因ID
- 2149
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NCBI登录号
- NP_001983
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UniProt
- P25116
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途径
- Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
抗原
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