Epidermal Keratin (AA 266-299) 抗体
This 小鼠 单克隆 antibody specifically detects Epidermal Keratin in IHC (fp), IHC (fro) 和 WB. It exhibits reactivity toward 人. It has been mentioned in 7+ publications
(7 references)
产品编号 ABIN4219252
发货至:
中国
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Quick Overview for Epidermal Keratin (AA 266-299) 抗体 (ABIN4219252)
抗原
Epidermal Keratin
适用
人
宿主
小鼠
克隆类型
单克隆
应用范围
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
克隆位点
AE3
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抗原表位
- AA 266-299
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特异性
- Most basic (type II) keratins
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交叉反应
- 牛, 小鸡, 人, 大鼠, 小鼠, 兔, 猴
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纯化方法
- Ion-exchange chromatography
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免疫原
- Human epidermal keratin
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亚型
- IgG1
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应用备注
- IHC: 1:100
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- reconstitue with 1 mL deionized water
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.4, 0.1 % sodum azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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: "Conformational changes in the rod domain of human keratin 8 following heterotypic association with keratin 18 and its implication for filament stability." in: Biochemistry, Vol. 43, Issue 5, pp. 1283-95, (2004) (PubMed).
: "Expression of cytokeratins in normal and neoplastic colonic epithelial cells. Implications for cellular differentiation and carcinogenesis." in: The American journal of surgical pathology, Vol. 10, Issue 12, pp. 829-35, (1986) (PubMed).
: "Nasopharyngeal carcinoma: immunohistochemical study for keratin, secretory component and leukocyte common antigen." in: Japanese journal of clinical oncology, Vol. 15, Issue 1, pp. 95-105, (1985) (PubMed).
: "Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes." in: The Journal of cell biology, Vol. 98, Issue 4, pp. 1397-406, (1984) (PubMed).
: "Antikeratin antibodies in tumor diagnosis. Distinction between seminoma and embryonal carcinoma." in: Cancer, Vol. 54, Issue 5, pp. 843-8, (1984) (PubMed).
: "Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies." in: The Journal of cell biology, Vol. 95, Issue 2 Pt 1, pp. 580-8, (1983) (PubMed).
: "Correlation of specific keratins with different types of epithelial differentiation: monoclonal antibody studies." in: Cell, Vol. 30, Issue 2, pp. 361-72, (1983) (PubMed).
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- Epidermal Keratin
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背景
- AE 3 represents an excellent marker fort distinguishing carcinoma from non-epithelial tumors. Tumors specifically detected: All epithelia and their neoplasms.
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分子量
- 53 - 67 kDa
抗原
-
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