SYT1 抗体 (Ser309)
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Quick Overview for SYT1 抗体 (Ser309) (ABIN401634)
抗原
See all SYT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser309
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特异性
- Synaptotagmin Antibody detects endogenous levels of total Synaptotagmin protein.
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纯化方法
- Affinity chromatography
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免疫原
- Synthesized non-phosphopeptide derived from human Synaptotagmin around the phosphorylation site of serine 309 (G-L-SP-D-P)
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应用备注
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Immunofluorescence: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- SYT1 (Synaptotagmin I (SYT1))
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别名
- Synaptotagmin-1
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背景
- Synaptotagmin 1 is a 60 kDa member of the synaptotagmin family, expressed in membranes of synaptic vesicles in rostral, phylogenetically younger brain regions and in some endocrine tissues. Ca2+ is bound by synaptogamin whose C2 domains then bind phospholipids, trafficking vesicles to the synaptic membrane and exocytosis. This results in fast synchronous neurotransmitter release. Synaptotagmin also binds neurexins, syntaxin and AP2 independently of Ca2+ binding. Phosphorylation of synaptotagmin by protein kinases is thought to modulate its activity.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
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基因ID
- 6857
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NCBI登录号
- NP_001129277
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UniProt
- P21579
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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