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SYT1 抗体 (Ser309)

This 兔 多克隆 anti-SYT1 antibody specifically detects SYT1 in WB 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN401634
发货至: 中国
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Quick Overview for SYT1 抗体 (Ser309) (ABIN401634)

抗原

See all SYT1 抗体
SYT1 (Synaptotagmin I (SYT1))

适用

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人, 大鼠, 小鼠

宿主

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  • 4
  • 1
  • 1

克隆类型

  • 98
  • 25
多克隆

标记

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This SYT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    Ser309

    特异性

    Synaptotagmin Antibody detects endogenous levels of total Synaptotagmin protein.

    纯化方法

    Affinity chromatography

    免疫原

    Synthesized non-phosphopeptide derived from human Synaptotagmin around the phosphorylation site of serine 309 (G-L-SP-D-P)
  • 应用备注

    Immunofluorescence: 1/100 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    SYT1 (Synaptotagmin I (SYT1))

    别名

    Synaptotagmin-1

    背景

    Synaptotagmin 1 is a 60 kDa member of the synaptotagmin family, expressed in membranes of synaptic vesicles in rostral, phylogenetically younger brain regions and in some endocrine tissues. Ca2+ is bound by synaptogamin whose C2 domains then bind phospholipids, trafficking vesicles to the synaptic membrane and exocytosis. This results in fast synchronous neurotransmitter release. Synaptotagmin also binds neurexins, syntaxin and AP2 independently of Ca2+ binding. Phosphorylation of synaptotagmin by protein kinases is thought to modulate its activity.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65

    基因ID

    6857

    NCBI登录号

    NP_001129277

    UniProt

    P21579

    途径

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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