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Tyrosine Hydroxylase 抗体 (pSer19)

This anti-Tyrosine Hydroxylase antibody is a 兔 多克隆 antibody detecting Tyrosine Hydroxylase in IF. Suitable for 大鼠.
产品编号 ABIN401584
发货至: 中国

Quick Overview for Tyrosine Hydroxylase 抗体 (pSer19) (ABIN401584)

抗原

See all Tyrosine Hydroxylase (TH) 抗体
Tyrosine Hydroxylase (TH)

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This Tyrosine Hydroxylase antibody is un-conjugated

应用范围

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Immunofluorescence (IF)
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    pSer19

    特异性

    Antibody AP09482PU detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at Serine 19.

    纯化方法

    Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    免疫原

    The antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Serine19 (A-V-Sp-E-Q).
  • 应用备注

    Immunofluorescence: 1/100approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at-20 °C.
  • 抗原

    Tyrosine Hydroxylase (TH)

    别名

    Tyrosine 3-Monooxygenase (TH)

    背景

    Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's diseaseSynonyms: TYH, Tyrosine 3-hydroxylase

    基因ID

    7054

    NCBI登录号

    NP_000351

    UniProt

    P07101

    途径

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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