TNKS2 抗体 (AA 800-900)
Our Local Distributor
北京 101111
Quick Overview for TNKS2 抗体 (AA 800-900) (ABIN401534)
抗原
See all TNKS2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 800-900
-
特异性
- This antibody detects Tankyrase-2 (TANK2). No cross-reactivity expected with TANK1.
-
交叉反应 （详细）
-
Species reactivity (expected):Mouse and Canine (Dog).
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Affinity Chromatography using the immunizing peptide.
-
免疫原
- Fusion protein containing 73 aa from aa 800-900 region of the protein sequence according to NP_079511.1. Genename: TNKS2
-
-
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (AA 1-246) antibody
TNKS2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (N-Term) antibodyTNKS2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (AA 1126-1156), (C-Term) antibodyTNKS2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB14166 unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (Internal Region) antibodyVerified TNKS2 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (Internal Region) antibodyVerified TNKS2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
- Western blot: 0.5-1.5 μg/mL. In transfected HEK293 transiently expressing TANK2 a band of approx.127 kDa is observed. This band is not observed in the non-transfected HEK293. The calculated molecular size is127 kDa according to NP_079511.1. Full caption (see picture below): HEK293 overexpressing TANK2 (lane 4) and TANK1 (lane 2)and probed with ABIN401534 (mock transfection in first lane). Lane three is empty. Lowerpanel shows the same lysates probed for alpha-Actin to show protein levels. Primaryincubation (0.5 μg/mL) was overnight at 4 °C. Detected by chemiluminescence.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- TNKS2 (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))
-
别名
- Tankyrase-2 (TANK2)
-
背景
- Tankyrase 2 may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. It has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length. Tankyrase 2 is highly expressed in placenta, skeletal muscle, liver, brain, kidney, heart, thymus, spinal cord, lung, peripheral blood leukocytes, pancreas, lymph nodes, spleen, prostate, testis, ovary, small intestine, colon, mammary gland, breast and breast carcinoma, and in common-type meningioma. Also highly expressed in fetal liver, heart and brain. Tankyrase 2 shares approximately 83 % sequence identity with Tankyrase 1.Synonyms: PARP5B, TNKL, TNKS-2, TNKS2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein
-
基因ID
- 80351
-
NCBI登录号
- NP_079511
-
UniProt
- Q9H2K2
抗原
-
