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MYB 抗体 (Internal Region)

The 兔 多克隆 anti-MYB antibody is suitable to detect MYB in samples from 人, 小鼠, 大鼠, 马, Pig, 猴, Bonobo, Chimpanzee, Gorilla, Opossum 和 Orang-Utan. It has been validated for WB 和 EIA.
产品编号 ABIN401456
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MYB 抗体 (Internal Region) (ABIN401456)

抗原

See all MYB 抗体
MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

适用

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人, 小鼠, 大鼠, 马, Pig, 猴, Bonobo, Chimpanzee, Gorilla, Opossum, Orang-Utan

宿主

  • 109
  • 22
  • 2
  • 2

克隆类型

  • 98
  • 37
多克隆

标记

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This MYB antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Internal Region

    特异性

    This antibody reacts with endogenous c-Myb protein and also SUMOylated overexpressed c-Myb protein in transfected Cos7 cells.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide corresponding to an internal portion of the c-Myb protein

    亚型

    IgG
  • 应用备注

    ELISA: 1/10,000 - 1/25,000. Western Blot: 1/250 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

    别名

    MYB

    背景

    The transcription factor c-Myb plays an important role in the development of all hematopoietic lineages during definitive hematopoiesis. Its critical role in hematopoiesis has been first demonstrated in experiments with targeted disruption of the c-Myb gene where deletion of both alleles of the c-Myb gene was embryonally lethal due to severe anemia. c-Myb is a short-lived sequence specific DNA-binding protein that regulates transcription of several important genes involved directly in cellular processes such as proliferation, differentiation, and apoptosis. Posttranslational modifications such as phosphorylation, acetylation, ubiquitination, and conjugation of SUMO proteins are crucial for modulation of the transactivation activity of c-Myb.Synonyms: Proto-oncogene c-Myb, Transcriptional activator Myb, c-Myb

    基因ID

    17863

    NCBI登录号

    NP_001185843

    UniProt

    P06876

    途径

    Chromatin Binding, Positive Regulation of Immune Effector Process
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