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MYB 抗体 (Internal Region)

MYB 适用: 人, 小鼠, 大鼠, 马, Pig, 猴, Opossum, Orang-Utan, Bonobo, Chimpanzee, Gorilla WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401455
发货至: 中国
  • 抗原 See all MYB 抗体
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    抗原表位
    • 15
    • 11
    • 11
    • 10
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 117
    • 52
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 马, Pig, 猴, Opossum, Orang-Utan, Bonobo, Chimpanzee, Gorilla
    宿主
    • 97
    • 21
    • 3
    • 3
    克隆类型
    • 103
    • 21
    多克隆
    标记
    • 80
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYB antibody is un-conjugated
    应用范围
    • 94
    • 58
    • 44
    • 24
    • 23
    • 13
    • 13
    • 12
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts with endogenous c-Myb protein and also SUMOylated overexpressed c-Myb protein in transfected Cos7 cells.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide corresponding to an internal portion of the c-Myb protein
    亚型
    IgG
    Top Product
    Discover our top product MYB Primary Antibody
  • 应用备注
    ELISA: 1/10,000 - 1/25,000. Western Blot: 1/250 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    别名
    MYB (MYB 产品)
    别名
    Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, AI550390 antibody, M16449 antibody, cmyb antibody, xmyb antibody, MYB proto-oncogene, transcription factor antibody, myeloblastosis oncogene antibody, MYB proto-oncogene, transcription factor S homeolog antibody, v-myb avian myeloblastosis viral oncogene homolog antibody, MYB antibody, Myb antibody, myb.S antibody, myb antibody
    背景
    The transcription factor c-Myb plays an important role in the development of all hematopoietic lineages during definitive hematopoiesis. Its critical role in hematopoiesis has been first demonstrated in experiments with targeted disruption of the c-Myb gene where deletion of both alleles of the c-Myb gene was embryonally lethal due to severe anemia. c-Myb is a short-lived sequence specific DNA-binding protein that regulates transcription of several important genes involved directly in cellular processes such as proliferation, differentiation, and apoptosis. Posttranslational modifications such as phosphorylation, acetylation, ubiquitination, and conjugation of SUMO proteins are crucial for modulation of the transactivation activity of c-Myb.Synonyms: Proto-oncogene c-Myb, Transcriptional activator Myb, c-Myb
    基因ID
    17863
    NCBI登录号
    NP_001185843
    UniProt
    P06876
    途径
    Chromatin Binding, Positive Regulation of Immune Effector Process
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