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PTENP1 抗体 (N-Term)

This anti-PTENP1 antibody is a 兔 多克隆 antibody detecting PTENP1 in WB 和 EIA. Suitable for 人, Chimpanzee, 犬, Macaque, 小鼠, 大鼠, Green Pufferfish 和 斑马鱼.
产品编号 ABIN401437
发货至: 中国

Quick Overview for PTENP1 抗体 (N-Term) (ABIN401437)

抗原

PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))

适用

人, Chimpanzee, 犬, Macaque, 小鼠, 大鼠, Green Pufferfish, 斑马鱼

宿主

  • 2
  • 2

克隆类型

  • 4
多克隆

标记

  • 4
This PTENP1 antibody is un-conjugated

应用范围

Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    N-Term

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Canine, Macaque, Chimpanzee, Opossum, Zebrafish, Green pufferfish, Platypus.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Purified peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein

    亚型

    IgG
  • 应用备注

    ELISA: 1/160,000. Western Blot: 1/500 to 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.73 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))

    别名

    PTENP1

    背景

    This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.Synonyms: PTEN-rs, PTEN2, PTH2, Phosphatase and tensin homolog 2, Phosphatase and tensin homolog pseudogene 1, psiPTEN

    基因ID

    9606

    UniProt

    O43460
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