SIPA1 抗体 (N-Term)
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北京 101111
Quick Overview for SIPA1 抗体 (N-Term) (ABIN401404)
抗原
See all SIPA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应 (详细)
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Species reactivity (expected):Human, Rat.
Species reactivity (tested):Mouse. -
纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide corresponding to a region near the amino terminus of mouse Sipa1
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亚型
- IgG
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应用备注
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ELISA: 1/20,000. Western Blot: 1/1,000 - 1/5,000. Immunohistochemistry: 1.25 - 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.25 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))
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别名
- SIPA1 / SPA1
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背景
- Sipa1 (signal-induced proliferation associated gene 1) is a mitogen-induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. Sipa1 is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.Synonyms: GTPase-activating protein Spa-1, Signal-induced proliferation-associated protein 1, Sipa-1, Spa-1, p130 SPA-1
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基因ID
- 10090
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UniProt
- P46062
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途径
- Response to Water Deprivation
抗原
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