RSL1D1 抗体 (Internal Region)
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北京 101111
Quick Overview for RSL1D1 抗体 (Internal Region) (ABIN401398)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody is specific for PBK1 protein.
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交叉反应 (详细)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide corresponding to an internal sequence of human PBK1
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亚型
- IgG
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应用备注
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ELISA: 1/2,500 - 1/10,000. WESTWestern Blot: 1/500 - 1/2,000. Immunoprecipitation: 1/100. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.1 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- RSL1D1 (Ribosomal L1 Domain Containing 1 (RSL1D1))
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别名
- RSL1D1
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背景
- PBK1 protein (also known as Ribosomal L1 domain-containing protein 1, cellular senescence-inhibited gene protein, and CATX-11) was isolated from highly invasive first trimester trophoblast cells and has been proposed to regulate their naturally occurring invasive behavior (Huch et al., 1998). PBK1 was also found to be over-expressed in non-small-cell lung cancer (NSCLC) cells (Petroziello et al., 2004). A recent study suggests that PBK1 may up-regulate the urokinase-type plasminogen activator (uPA) gene, which plays an important role in cellular matrix degradation and activation of other protease systems involved in cell invasion (Tong et al., 2005). PBK1 shows a nuclear and nucleolar localization.Synonyms: CATX-11, CSIG, Cellular senescence-inhibited gene protein, PBK1, Ribosomal L1 domain-containing protein 1
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基因ID
- 26156
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NCBI登录号
- NP_056474
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UniProt
- O76021
抗原
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