GPX4 抗体 (C-Term)
Quick Overview for GPX4 抗体 (C-Term) (ABIN401375)
抗原
See all GPX4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is directed against GPx4 protein.
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交叉反应 （详细）
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Species reactivity (expected):Rat, Guinea Pig, Human.
Species reactivity (tested):Mouse. -
纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide corresponding to amino acids near the carboxyl terminus of mouse GPx4 protein
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亚型
- IgG
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anti-Glutathione Peroxidase 4 (GPX4) (AA 30-197) antibody
GPX4 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibodyGPX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibodyGPX4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibodyGPX4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibodyVerified GPX4 适用: 人 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) antibodyKO Validated GPX4 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibodyGPX4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 72-121) antibodyGPX4 适用: 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, Cow, 猴, 山羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 81-93) antibodyGPX4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) antibodyGPX4 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/7,000 - 1/30,000. Western Blot: 1/500 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.15 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- GPX4 (Glutathione Peroxidase 4 (GPX4))
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别名
- Glutathione Peroxidase 4 / GPX4
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背景
- Glutathione Peroxidase 4 (GPx4, also known as PHGPx) functions as an antioxidant and also plays a role in redox regulation, sexual maturation, inflammation, apoptosis, and differentiation. GPx4 was found to have an important role in preventing lipid peroxidation, and has been discussed primarily as the glutathione peroxidase protecting biomembranes against oxidative stress. GPx4 can react with free hydrogen peroxide as well as with a wide range of lipid hydroperoxides, including those derived from cholesterol and cholesteryl esters. GPx4 is the only GPx to use phospholipid hydroperoxides as substrates. It can also reduce thymine hydroperoxide. In contrast to GPx1 and GPx3, GPx4 can use a wide range of reducing substrates in addition to glutathione. GPx4 is expressed in high levels in testes, suggesting a role in male fertility. It has also been identified as an enzymatically inactive structural protein of the mitochondrial capsule of sperm.Synonyms: GPx-4, Phospholipid hydroperoxide glutathione peroxidase mitochondrial
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基因ID
- 2879
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NCBI登录号
- NP_001034936
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UniProt
- P36969
抗原
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