APC1 抗体 (pSer355)
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Quick Overview for APC1 抗体 (pSer355) (ABIN401294)
抗原
See all APC1 (ANAPC1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-359, pSer355
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特异性
- This antibody is specific for phosphorylated APC1 protein at the pS355 residue.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine, Bovine, Chimpanzee, Chicken.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide corresponding to amino acids 351-359 of Human Apc1 protein
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亚型
- IgG
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应用备注
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ELISA: 1/10,000 - 1/40,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.55 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))
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别名
- APC1 / ANAPC1
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背景
- APC1 (also known as Anaphase promoting complex subunit 1, Cyclosome subunit 1, Protein Tsg24, Mitotic checkpoint regulator and ANAPC1) is 1 of at least 11 subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.Synonyms: Anaphase-promoting complex subunit 1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24, Testis-specific gene 24 protein
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基因ID
- 64682
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NCBI登录号
- NP_073153
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UniProt
- Q9H1A4
抗原
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