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ZIC2 抗体 (AA 189-206)

This 兔 多克隆 antibody specifically detects ZIC2 in WB 和 EIA. It exhibits reactivity toward 人, 大鼠, 小鼠, 犬 和 Chimpanzee.
产品编号 ABIN401287
发货至: 中国
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Quick Overview for ZIC2 抗体 (AA 189-206) (ABIN401287)

抗原

See all ZIC2 抗体
ZIC2

适用

  • 20
  • 15
  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠, 犬, Chimpanzee

宿主

  • 32
  • 2
  • 1

克隆类型

  • 33
  • 2
多克隆

标记

  • 12
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This ZIC2 antibody is un-conjugated

应用范围

  • 24
  • 13
  • 13
  • 9
  • 7
  • 3
  • 3
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 189-206

    特异性

    This antibody is directed against Mouse ZIC2 protein. A BLAST analysis was used to suggest reactivity with this protein from Human, Chimpanzee, Mouse, Rat and Dog based on 100 % homology for the immunogen sequence. Expect cross reactivity with ZIC2 from Chicken, Zebrafish and Frog as the core 16 amino acid residues within the immunogen sequence show very high degrees of homology with ZIC2 from these sources. Cross reactivity with ZIC2 homologues from other sources has not been determined.

    交叉反应 (详细)

    Species reactivity (expected):Human, Chimpanzee, Mouse, Rat, Canine, Chicken, Zebrafish, Frog.
    Species reactivity (tested):Mouse.

    纯化方法

    Affinity Chromatography

    免疫原

    Synthetic peptide corresponding amino acids 189-206 of Mouse ZIC-2

    亚型

    IgG
  • 应用备注

    ELISA: 1/10,000 - 1/50,000. Western Blot: 1/500 - 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at-20 °C.
  • 抗原

    ZIC2

    别名

    ZIC2

    背景

    ZIC2 (also known as zinc finger protein of the cerebellum 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog) is a nuclear protein that functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.Synonyms: Zinc finger protein ZIC 2, Zinc finger protein of the cerebellum 2

    基因ID

    7546

    NCBI登录号

    NP_009060

    UniProt

    O95409

    途径

    Tube Formation
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