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SLIT2 抗体 (AA 484-500)

SLIT2 适用: 人, 大鼠, 小鼠, 小鸡, Cow, Tetraodon nigroviridis, 非洲爪蟾 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401286
发货至: 中国
  • 抗原 See all SLIT2 抗体
    SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
    抗原表位
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 484-500
    适用
    人, 大鼠, 小鼠, 小鸡, Cow, Tetraodon nigroviridis, 非洲爪蟾
    宿主
    • 48
    • 3
    • 2
    • 1
    克隆类型
    • 51
    • 3
    多克隆
    标记
    • 22
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLIT2 antibody is un-conjugated
    应用范围
    • 45
    • 23
    • 14
    • 13
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is directed against SLIT-2 protein.
    交叉反应 (详细)
    Species reactivity (expected):Chicken, Mouse, Rat, Bovine, Xenopus laevis.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography
    免疫原
    Synthetic peptide corresponding aa 484-500 of Human SLIT-2 protein.
    亚型
    IgG
    Top Product
    Discover our top product SLIT2 Primary Antibody
  • 应用备注
    ELISA: 1/1,500 - 1/6,000. Western Blot: 1/500 - 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted 2-8 °C fo one month or (in aliquots) at-20 °C for longer.
  • 抗原
    SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
    别名
    SLIT2 (SLIT2 产品)
    别名
    SLIL3 antibody, Slit-2 antibody, Drad-1 antibody, E030015M03Rik antibody, E130320P19Rik antibody, Slil3 antibody, mKIAA4141 antibody, Slit antibody, slil3 antibody, slit-2 antibody, slit2-a antibody, SLIT2 antibody, slit guidance ligand 2 antibody, slit homolog 2 (Drosophila) antibody, slit guidance ligand 2 S homeolog antibody, SLIT2 antibody, Slit2 antibody, slit2 antibody, slit2.S antibody
    背景
    SLIT-2 is thought to act as a molecular guidance cue in cellular migration, and its function appears to be mediated by interaction with roundabout homologue receptors. SLIT-1 and SLIT-2 seem to be essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development SLIT-2 may play role in guiding commissural axons once they reach the floor plate by modulating the response to netrin. In vitro, SLIT-2 silences the attractive effect of NTN1 but not its growthstimulatory effect and silencing requires the formation of a ROBO1-DCC complex. In vitro, only commissural axons that crossed the midline responded to SLIT-2. In the developing visual system this protein functions as a repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. SLIT-2 is a secreted protein predominantly expressed in fetal lung and kidney, and adult spinal cord. Weak expression is observed in adult adrenal gland, thyroid, trachea and other tissues examined. Multiple isoforms have been reported for this product.Synonyms: SLIL3, SLIT-2, Slit homolog 2 protein
    基因ID
    9353
    NCBI登录号
    NP_004778
    UniProt
    O94813
    途径
    Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration
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