电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SLIT2 抗体 (AA 484-500)

The 兔 多克隆 anti-SLIT2 antibody (ABIN401286) specifically detects SLIT2 in WB 和 EIA. The antibody is reactive with 人, 小鼠, 大鼠, 小鸡, Cow, Tetraodon nigroviridis 和 非洲爪蟾 samples.
产品编号 ABIN401286
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SLIT2 抗体 (AA 484-500) (ABIN401286)

抗原

See all SLIT2 抗体
SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

适用

人, 小鼠, 大鼠, 小鸡, Cow, Tetraodon nigroviridis, 非洲爪蟾

宿主

  • 67
  • 3
  • 1
  • 1

克隆类型

  • 57
  • 15
多克隆

标记

  • 31
  • 12
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SLIT2 antibody is un-conjugated

应用范围

  • 63
  • 35
  • 22
  • 15
  • 13
  • 13
  • 11
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 484-500

    特异性

    This antibody is directed against SLIT-2 protein.

    交叉反应 (详细)

    Species reactivity (expected):Chicken, Mouse, Rat, Bovine, Xenopus laevis.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography

    免疫原

    Synthetic peptide corresponding aa 484-500 of Human SLIT-2 protein.

    亚型

    IgG
  • 应用备注

    ELISA: 1/1,500 - 1/6,000. Western Blot: 1/500 - 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted 2-8 °C fo one month or (in aliquots) at-20 °C for longer.
  • 抗原

    SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

    别名

    SLIT2

    背景

    SLIT-2 is thought to act as a molecular guidance cue in cellular migration, and its function appears to be mediated by interaction with roundabout homologue receptors. SLIT-1 and SLIT-2 seem to be essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development SLIT-2 may play role in guiding commissural axons once they reach the floor plate by modulating the response to netrin. In vitro, SLIT-2 silences the attractive effect of NTN1 but not its growthstimulatory effect and silencing requires the formation of a ROBO1-DCC complex. In vitro, only commissural axons that crossed the midline responded to SLIT-2. In the developing visual system this protein functions as a repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. SLIT-2 is a secreted protein predominantly expressed in fetal lung and kidney, and adult spinal cord. Weak expression is observed in adult adrenal gland, thyroid, trachea and other tissues examined. Multiple isoforms have been reported for this product.Synonyms: SLIL3, SLIT-2, Slit homolog 2 protein

    基因ID

    9353

    NCBI登录号

    NP_004778

    UniProt

    O94813

    途径

    Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration
You are here: