WRNIP1 抗体 (Internal Region)
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Quick Overview for WRNIP1 抗体 (Internal Region) (ABIN401271)
抗原
See all WRNIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody detects WHIP1. Cross reactivity with WHIP2 protein (isoform2) from human sources is expected based on high homology (BLAST).
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交叉反应 (详细)
- Species reactivity (expected):Mouse, Rat, Monkey (100 %)Species reactivity (tested):Human.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Synthetic peptide corresponding to an internal region of the WHIP1 protein
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亚型
- IgG
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应用备注
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ELISA: 1: 10,000 - 1: 40,000. Western blot: 1: 500 - 1: 2,000, detects a band of approximately 96.0 kDa (predictedmolecular weight: 72.2 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.10 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
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别名
- ATPase WRNIP1
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背景
- Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. Werner helicase interacting protein 1 (WHIP) interacts with the N-terminal portion of Werner protein, which contains an exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene product may influence the aging process. A second isoform exists (WHIP2).Synonyms: WHIP, WRNIP1, Werner helicase-interacting protein 1
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基因ID
- 56897
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NCBI登录号
- NP_064520
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UniProt
- Q96S55
抗原
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