CENPQ 抗体
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北京 101111
Quick Overview for CENPQ 抗体 (ABIN401060)
抗原
See all CENPQ 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is specific for CENP-Q protein.
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交叉反应 (详细)
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Species reactivity (expected):Macaque, Horse, Bovine, Canine, Porcine, Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography on protein A
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免疫原
- Prepared from whole rabbit serum produced by repeated immunizations with full-length human CENP-Q recombinant protein
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亚型
- IgG
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应用备注
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ELISA: 1: 20,000 - 1: 30,000. Immunofluorescence. Western Blot: 1: 2,000 - 1: 2,500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.15 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- CENPQ (Centromere Protein Q (CENPQ))
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别名
- CENP-Q
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背景
- Cenp-Q (also known as centromere protein Q or CENPQ) is a nuclear/centromeric protein that is one of the critical components that constitutes the CENP-O complex at the kinetochores and appears to stabilize PBIP1/CENP-U(50)/MLF1IP in the complex. This complex is important for proper recruitment of polo-like kinase 1 (Plk1) to the mitotic kinetochores. A failure in this process results in improper microtubule attachment to the kinetochores and chromosome missegregation that ultimately lead to aneuploidy.Synonyms: C6orf139, CENPQ, Centromere protein Q, chromosome 6 open reading frame 139
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基因ID
- 55166
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NCBI登录号
- NP_060602
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UniProt
- Q7L2Z9
抗原
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