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CENPQ 抗体

The 兔 多克隆 anti-CENPQ antibody is suitable to detect CENPQ in samples from 人, 小鼠, 大鼠, Cow, 犬, 马, Macaque 和 Pig. It has been validated for WB, IF 和 EIA.
产品编号 ABIN401060
发货至: 中国
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Quick Overview for CENPQ 抗体 (ABIN401060)

抗原

See all CENPQ 抗体
CENPQ (Centromere Protein Q (CENPQ))

适用

人, 小鼠, 大鼠, Cow, 犬, 马, Macaque, Pig

宿主

  • 8
  • 1

克隆类型

  • 8
  • 1
多克隆

标记

  • 9
This CENPQ antibody is un-conjugated

应用范围

  • 8
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody is specific for CENP-Q protein.

    交叉反应 (详细)

    Species reactivity (expected):Macaque, Horse, Bovine, Canine, Porcine, Mouse, Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on protein A

    免疫原

    Prepared from whole rabbit serum produced by repeated immunizations with full-length human CENP-Q recombinant protein

    亚型

    IgG
  • 应用备注

    ELISA: 1: 20,000 - 1: 30,000. Immunofluorescence. Western Blot: 1: 2,000 - 1: 2,500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.15 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    CENPQ (Centromere Protein Q (CENPQ))

    别名

    CENP-Q

    背景

    Cenp-Q (also known as centromere protein Q or CENPQ) is a nuclear/centromeric protein that is one of the critical components that constitutes the CENP-O complex at the kinetochores and appears to stabilize PBIP1/CENP-U(50)/MLF1IP in the complex. This complex is important for proper recruitment of polo-like kinase 1 (Plk1) to the mitotic kinetochores. A failure in this process results in improper microtubule attachment to the kinetochores and chromosome missegregation that ultimately lead to aneuploidy.Synonyms: C6orf139, CENPQ, Centromere protein Q, chromosome 6 open reading frame 139

    基因ID

    55166

    NCBI登录号

    NP_060602

    UniProt

    Q7L2Z9
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