ENPP3 抗体 (PE)
Our Local Distributor
北京 101111
Quick Overview for ENPP3 抗体 (PE) (ABIN400883)
抗原
See all ENPP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- The antibody NP4D6 reacts with CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
-
产品特性
- Synonyms: E-NPP 3, PDNP3, Phosphodiesterase I beta, PD-I beta, Ectonucleotide pyrophosphatase /phosphodiesterase family member 3, Phosphodiesterase I/nucleotide pyrophosphatase 3
-
纯化方法
- Size-Exclusion Chromatography
-
免疫原
- HEK-293 cells transfected with human CD203c
-
亚型
- IgG1
-
-
-
-
应用备注
-
Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 mLof whole bloodor 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS, 15 mM Sodium Azide, 0.2 % high-grade protease free BSA as a stabilizing agent
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
-
Store at 2-8 °C. Do not freeze. This antibody is photosensitive and should be protected fromlight.
Shelf life: One year from despatch. -
有效期
- 12 months
-
-
- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
-
别名
- CD203c / ENPP3
-
背景
- CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.Synonyms: E-NPP 3, Ectonucleotide pyrophosphatase / phosphodiesterase family member 3, PD-I beta, PDNP3, Phosphodiesterase I beta, Phosphodiesterase I/nucleotide pyrophosphatase 3
-
基因ID
- 5169
-
UniProt
- O14638
-
途径
- Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
抗原
-