BRCC3 抗体 (N-Term)
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Quick Overview for BRCC3 抗体 (N-Term) (ABIN400864)
抗原
See all BRCC3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-316, N-Term
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特异性
- The antibody recognizes human BRCC3 / BRCC36. Other species not tested.
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产品特性
- Synonyms: BRCC36, C6.1A, CXorf53, Lys-63-specific deubiquitinase BRCC36, BRCA1-A complex subunitBRCC36, BRISC complex subunit BRCC36, BRCA1/BRCA2-containing complex subunit 3,BRCA1/BRCA2-containing complex subunit 36
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纯化方法
- Protein-G affinity chromatography
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免疫原
- Recombinant BRCC36 (1-316 aa) purified from E. coli
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亚型
- IgG1
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应用备注
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ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on Paraffin Sections: (5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))
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别名
- BRCC3
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背景
- BRCC3 (BRCC36, BRCA1/BRCA2-containing complex, subunit 36) is a holoenzyme complex containing BRCA1, BRCA2. BRCC36 is an ubiquitin E3 ligase complex that has a role in DNA repair and enhances cellular survival following DNA damage. This protein is also thought to be involved in the cellular response to ionizing radiation and progression through the G2/M checkpoint.Synonyms: BRCA1-A complex subunit BRCC36, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRCC36, BRISC complex subunit BRCC36, C6.1A, CXorf53, Lys-63-specific deubiquitinase BRCC36
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基因ID
- 79184
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UniProt
- P46736
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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