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HAX1 抗体 (N-Term)

The 小鼠 单克隆 anti-HAX1 antibody is suitable to detect HAX1 in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN400856
发货至: 中国
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Quick Overview for HAX1 抗体 (N-Term) (ABIN400856)

抗原

See all HAX1 抗体
HAX1 (HCLS1 Associated Protein X-1 (HAX1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This HAX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

AT3C5
  • 抗原表位

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    AA 1-279, N-Term

    特异性

    The antibody recognizes human HAX-1. Other species not tested.

    产品特性

    Synonyms: HAX-1, HS1BP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-bindingprotein 1

    纯化方法

    Protein-G affinity chromatography

    免疫原

    Recombinant human HAX1 (1-279 aa) purified from E. coli

    亚型

    IgG2b
  • 应用备注

    ELISA. Western blot (1: 1000 - 1: 2000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    HAX1 (HCLS1 Associated Protein X-1 (HAX1))

    别名

    HAX1

    背景

    HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1 (HS1), one of the substrates of receptor-coupled tyrosine kinases activated during clonal expansion and deletion in lymphoid cells. It also interacts with the product of the polycystic kidney disease 2 (PKD2) gene and with the F-actin-binding protein, cortactin. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1

    基因ID

    10456

    UniProt

    O00165

    途径

    Regulation of Actin Filament Polymerization
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