Glutathione Peroxidase 1 抗体
Quick Overview for Glutathione Peroxidase 1 抗体 (ABIN400775)
抗原
See all Glutathione Peroxidase 1 (GPX1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes Glutathione Peroxidase (GPX1).
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交叉反应 (详细)
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Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse. -
产品特性
- Synonyms: GSHPx-1, Cellular glutathione peroxidase
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纯化方法
- Purified
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免疫原
- Recombinant Mouse protein purified from E. coli (Gpx1).
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亚型
- IgG1
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应用备注
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ELISA. Western Blot: 1/5000. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- HEPES containing 0.15 M Sodium Chloride, 0.01 % BSA as stabilizer, 0.03 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Glutathione Peroxidase 1 (GPX1)
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别名
- Glutathione Peroxidase 1 / GPX1
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背景
- Glutathione peroxidases(GPxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. This protein is one of the most important antioxidant enzymes in humans. This protein has been reported to protect cultured breast cancer cells from CD95-induced apoptosis and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges. There are several isoforms which differ in their primary structure and localization. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis specific secretory GPx(eGPxor GPx5)isoforms, possess selenocysteine at the active site. One allele of the Glutathione Peroxidase 1 gene is significantly associated with an increased breast cancer risk.Synonyms: Cellular glutathione peroxidase, GSHPx-1
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基因ID
- 2876
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UniProt
- P07203
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途径
- Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
抗原
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