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Glutathione Peroxidase 1 抗体

This anti-Glutathione Peroxidase 1 antibody is a 小鼠 单克隆 antibody detecting Glutathione Peroxidase 1 in WB, IP, IHC (p) 和 EIA. Suitable for 人 和 大鼠.
产品编号 ABIN400775
发货至: 中国

Quick Overview for Glutathione Peroxidase 1 抗体 (ABIN400775)

抗原

See all Glutathione Peroxidase 1 (GPX1) 抗体
Glutathione Peroxidase 1 (GPX1)

适用

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人, 大鼠

宿主

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  • 4
  • 2
  • 1
小鼠

克隆类型

  • 48
  • 19
单克隆

标记

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  • 1
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This Glutathione Peroxidase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

克隆位点

13B2AF
  • 特异性

    Recognizes Glutathione Peroxidase (GPX1).

    交叉反应 (详细)

    Species reactivity (expected):Human and Rat.
    Species reactivity (tested):Mouse.

    产品特性

    Synonyms: GSHPx-1, Cellular glutathione peroxidase

    纯化方法

    Purified

    免疫原

    Recombinant Mouse protein purified from E. coli (Gpx1).

    亚型

    IgG1
  • 应用备注

    ELISA. Western Blot: 1/5000. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    HEPES containing 0.15 M Sodium Chloride, 0.01 % BSA as stabilizer, 0.03 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Glutathione Peroxidase 1 (GPX1)

    别名

    Glutathione Peroxidase 1 / GPX1

    背景

    Glutathione peroxidases(GPxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. This protein is one of the most important antioxidant enzymes in humans. This protein has been reported to protect cultured breast cancer cells from CD95-induced apoptosis and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges. There are several isoforms which differ in their primary structure and localization. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis specific secretory GPx(eGPxor GPx5)isoforms, possess selenocysteine at the active site. One allele of the Glutathione Peroxidase 1 gene is significantly associated with an increased breast cancer risk.Synonyms: Cellular glutathione peroxidase, GSHPx-1

    基因ID

    2876

    UniProt

    P07203

    途径

    Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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