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CCL5 抗体

CCL5 适用: 人 Neut, IHC (p), EIA 宿主: 小鼠 Monoclonal 8-PP-11 unconjugated
产品编号 ABIN400758
发货至: 中国
  • 抗原 See all CCL5 抗体
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    适用
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    小鼠
    克隆类型
    • 99
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    单克隆
    标记
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    This CCL5 antibody is un-conjugated
    应用范围
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    Neutralization (Neut), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes Human RANTES. The antibody effectively inhibits Chemotaxis of Human Monocytes, Human Lymphocytes and Rat peritoneal Macrophages induced by Human RANTES.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    产品特性
    Synonyms: C-C motif chemokine 5, D17S136E, SCYA5, Small-inducible cytokine A5, SIS-delta, EoCP,T-cell-specific protein RANTES, cell-specific protein P228, Eosinophil-chemotactic cytokine
    纯化方法
    Protein A Chromatography.
    免疫原
    RANTES
    克隆位点
    8-PP-11
    亚型
    IgG2b
    Top Product
    Discover our top product CCL5 Primary Antibody
  • 应用备注
    ELISA: 2-4 μg/mL. Neutralization. Immunohistochemistry on Paraffin Sections: 5 μg/mL. This CCL5 antibody was validated for use in Immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) Human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by AlkalinePhosphatase-streptavidin and chromogen.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2 containing 40 % Glycerol without preservatives.
    储存液
    Without preservative
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    别名
    RANTES / CCL5 (CCL5 产品)
    别名
    Rantes antibody, Scya5 antibody, D17S136E antibody, RANTES antibody, SCYA5 antibody, SIS-delta antibody, SISd antibody, TCP228 antibody, eoCP antibody, MuRantes antibody, C-C motif chemokine 5-like antibody, C-C motif chemokine ligand 5 antibody, chemokine (C-C motif) ligand 5 antibody, LOC100230935 antibody, CCL5 antibody, Ccl5 antibody
    背景
    RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV). It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.Synonyms: C-C motif chemokine 5, D17S136E, E °CP, Eosinophil-chemotactic cytokine, SCYA5, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES, cell-specific protein P228
    基因ID
    6352
    UniProt
    P13501
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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