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CD147 抗体

BSG 适用: 人, Pig FACS, IHC (p) 宿主: 小鼠 Monoclonal MEM-M6-2 unconjugated
产品编号 ABIN400674
发货至: 中国
  • 抗原 See all CD147 (BSG) 抗体
    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
    适用
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    人, Pig
    宿主
    • 84
    • 78
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    小鼠
    克隆类型
    • 96
    • 71
    • 3
    单克隆
    标记
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    This CD147 antibody is un-conjugated
    应用范围
    • 93
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    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    AM08322PU-N recognizes extracellular Ig domain D1 of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells, it is not expressed by resting lymphocytes. This antibody is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
    交叉反应 (详细)
    Species reactivity (expected):Porcine.
    Species reactivity (tested):Human.
    产品特性
    Synonyms: Basigin, BSG, EMMPRIN, TCSF, Leukocyte activation antigen M6, Collagenase stimulatoryfactor, Extracellular matrix metalloproteinase inducer, 5F7, Tumor cell-derived collagenasestimulatory factor, OK blood group antigen
    纯化方法
    Protein A Chromatography.
    免疫原
    A soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for theentire extracellular region of CD147 fused to the DNA coding for the hinge region, CH2 andCH3 domain of human IgG1
    克隆位点
    MEM-M6-2
    亚型
    IgG2b
    Top Product
    Discover our top product BSG Primary Antibody
  • 应用备注
    Flow Cytometry. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4 containing 15 mM Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
    别名
    CD147 (BSG 产品)
    背景
    CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3, probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor
    基因ID
    682
    UniProt
    P35613
    途径
    S100 Proteins
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