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CD22 抗体

CD22 适用: 人 FACS 宿主: 小鼠 Monoclonal IS7 unconjugated
产品编号 ABIN400636
发货至: 中国
  • 抗原 See all CD22 抗体
    CD22 (CD22 Molecule (CD22))
    适用
    • 140
    • 56
    • 23
    • 5
    • 3
    • 2
    • 2
    • 1
    宿主
    • 90
    • 66
    • 16
    • 1
    小鼠
    克隆类型
    • 114
    • 57
    • 1
    单克隆
    标记
    • 91
    • 14
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    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD22 antibody is un-conjugated
    应用范围
    • 104
    • 75
    • 48
    • 37
    • 35
    • 19
    • 12
    • 12
    • 11
    • 6
    • 5
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    Flow Cytometry (FACS)
    交叉反应 (详细)
    Species reactivity (tested):Human
    产品特性
    Synonyms: SIGLEC2, Siglec-2, B-cell receptor CD22, Leu-14, BL-CAM, Sialic acid-binding Ig-like lectin 2,B-lymphocyte cell adhesion molecule
    纯化方法
    Protein A affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    免疫原
    Reh human cell line
    克隆位点
    IS7
    亚型
    IgG1
    Top Product
    Discover our top product CD22 Primary Antibody
  • 应用备注
    Flow Cytometry. Positive control: lysed whole blood.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized.
    储存液
    Azide free
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD22 (CD22 Molecule (CD22))
    别名
    CD22 (CD22 产品)
    背景
    CD22, also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2,6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs), thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.Synonyms: B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14, SIGLEC2, Sialic acid-binding Ig-like lectin 2, Siglec-2
    UniProt
    P20273
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