电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

DUSP14 抗体 (N-Term)

This anti-DUSP14 antibody is a 兔 多克隆 antibody detecting DUSP14 in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN392877
发货至: 中国

Quick Overview for DUSP14 抗体 (N-Term) (ABIN392877)

抗原

See all DUSP14 抗体
DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

适用

  • 43
  • 15
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 36
  • 6
  • 1

克隆类型

  • 39
  • 4
多克隆

标记

  • 21
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DUSP14 antibody is un-conjugated

应用范围

  • 31
  • 28
  • 17
  • 5
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB5911
  • 抗原表位

    • 6
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    AA 1-30, N-Term

    预测反应

    B

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This DUSP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DUSP14.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

    别名

    DUSP14

    背景

    DUSP14 is involved in the inactivation of MAP kinases. This protein dephosphorylates ERK, JNK and p38 MAP-kinases. In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28, which interacts with B7-1 and B7-2 ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK and JNK, and the subsequent creation of AP1 transcription factor. DUSP14 is a negative regulator of CD28 signaling.

    分子量

    22255

    基因ID

    11072

    NCBI登录号

    NP_008957

    UniProt

    O95147
You are here:
Chat with us!