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DUSP6 抗体 (AA 58-89)

This anti-DUSP6 antibody is a 兔 多克隆 antibody detecting DUSP6 in WB, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN392864
发货至: 中国

Quick Overview for DUSP6 抗体 (AA 58-89) (ABIN392864)

抗原

See all DUSP6 抗体
DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

适用

  • 95
  • 58
  • 51
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 82
  • 12
  • 2
  • 1

克隆类型

  • 76
  • 21
多克隆

标记

  • 45
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DUSP6 antibody is un-conjugated

应用范围

  • 63
  • 32
  • 19
  • 16
  • 11
  • 9
  • 9
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB05814
  • 抗原表位

    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 58-89

    预测反应

    B

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DUSP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-89 amino acids from the Central region of human DUSP6.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:2000. WB: 1:500. WB: 1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

    别名

    DUSP6

    背景

    DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for the DUSP6 gene.

    分子量

    42320

    基因ID

    1848

    NCBI登录号

    NP_001937, NP_073143

    UniProt

    Q16828

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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