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PFKFB2 抗体 (N-Term)

Name: PFKFB2 抗体 (N-Term)
SKU: ABIN392769
Availability: OutOfStock

Cited in 3+ publications. This 兔多克隆 anti-PFKFB2 antibody (Clone RB4031-4032) specifically detects PFKFB2 in WB 和 IHC (p). The antibody is reactive with 人 samples.

Western blot analysis of anti-PFKFB2 Pab (ABIN392769 and ABIN2842214) in mouse kidney tissue lysate (35 μg/lane). (PFKFB2 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PFKFB2 抗体 (N-Term))

IHC (p)

2 images

(3 references)

产品编号 ABIN392769

发货至: 中国

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Quick Overview for PFKFB2 抗体 (N-Term) (ABIN392769)

抗原

See all PFKFB2 抗体

PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PFKFB2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB4031-4032

Discover our top product PFKFB2 Primary Antibody

抗原表位
15

12

7

7

7

6

6

3

2

1

1

1

1

1

1

1

1

1

1

1
AA 1-30, N-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This PFKFB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PFKFB2.

亚型

Ig Fraction
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 446-505) antibody
PFKFB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 360-505) antibody
PFKFB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (pSer483) antibody
PFKFB2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 467-497), (C-Term) antibody
PFKFB2 适用: 人 WB 宿主: 兔 Polyclonal RB4033 unconjugated

anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (C-Term) antibody
PFKFB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (pSer483) antibody
PFKFB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (C-Term) antibody
PFKFB2 适用: 人, 小鼠, 大鼠, 猴, 犬, 马, 豚鼠, 兔, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated

anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 336-385) antibody
PFKFB2 适用: 人, 小鼠, 大鼠, 猴, 犬, 马, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated

anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (N-Term) antibody
PFKFB2 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (N-Term) antibody
PFKFB2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

有效期

6 months
Xia, Hong, Ye, Wang, Chen, Liu: "Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients." in: Journal of proteomics, Vol. 84, pp. 78-91, (2013) (PubMed).

Carlet, Janjetovic, Rainer, Schmidt, Panzer-Grümayer, Mann, Prelog, Meister, Ploner, Kofler: "Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells." in: BMC cancer, Vol. 10, pp. 638, (2010) (PubMed).

Yalcin, Clem, Simmons, Lane, Nelson, Clem, Brock, Siow, Wattenberg, Telang, Chesney: "Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 24223-32, (2009) (PubMed).
抗原

PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

别名

PFKFB2

背景

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

分子量

58477

NCBI登录号

NP_001018063, NP_006203

UniProt

O60825

途径

PI3K-Akt Signaling, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process