This anti-Adenylate Kinase 5 antibody is a 兔 多克隆 antibody detecting Adenylate Kinase 5 in WB 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This AK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-433 amino acids from the N-terminal region of human AK5.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
Saito, Kitamura, Hijikata, Tomizawa-Murasawa, Tanaka, Takagi, Uchida, Suzuki, Sone, Najima, Ozawa, Wake, Taniguchi, Shultz, Ohara, Ishikawa: "Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells." in: Science translational medicine, Vol. 2, Issue 17, pp. 17ra9, (2010) (PubMed).
抗原
Adenylate Kinase 5 (AK5)
别名
AK5
背景
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).