DGKQ 抗体 (C-Term)
Quick Overview for DGKQ 抗体 (C-Term) (ABIN392717)
抗原
See all DGKQ 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 912-942, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This DGKQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 912-942 amino acids from the C-terminal region of human DGKQ.
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亚型
- Ig Fraction
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anti-Diacylglycerol Kinase, theta 110kDa (DGKQ) (C-Term) antibody
DGKQ 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Diacylglycerol Kinase, theta 110kDa (DGKQ) (AA 751-800) antibodyDGKQ 适用: 人, 小鼠, 大鼠, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Diacylglycerol Kinase, theta 110kDa (DGKQ) antibodyDGKQ 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Diacylglycerol Kinase, theta 110kDa (DGKQ) (C-Term) antibodyDGKQ 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Diacylglycerol Kinase, theta 110kDa (DGKQ) (Middle Region) antibodyDGKQ 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))
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别名
- DGKQ
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背景
- Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid.The predicted 882-amino acid human DGKQ (DGK-theta) protein is 90 % identical in sequence to the rat homolog. DGK-theta is comprised of a pleckstrin homology domain and the conserved DGK putative catalytic domain. In contrast to other DGK isotypes, DGK-theta contains 3 rather than 2 cysteine-rich zinc-binding domains, an N-terminal proline- and glycine-rich region, and a RAS-associating domain. Highest tissue expression in the rat is in the brain. Defects in eye-specific DAGK genes cause retinal degeneration in Drosophila, thus, DAGK genes are candidates for human eye disease.
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分子量
- 101155
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基因ID
- 1609
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NCBI登录号
- NP_001338
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UniProt
- P52824
抗原
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