PACSIN2 抗体 (C-Term)
(10 references)Quick Overview for PACSIN2 抗体 (C-Term) (ABIN392666)
抗原
See all PACSIN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 342-371, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PACSIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human PACSIN2.
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亚型
- Ig Fraction
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anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (AA 240-410) antibody
PACSIN2 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (AA 368-428) antibodyPACSIN2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3D6 unconjugated
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) antibodyPACSIN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (AA 342-371) antibodyPACSIN2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) antibodyPACSIN2 适用: 人, 小鼠 WB, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (AA 250-486) antibodyPACSIN2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1735CT116-76-60 unconjugated
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (AA 1-486) antibodyPACSIN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (AA 1-486) antibodyPACSIN2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (C-Term) antibodyPACSIN2 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:25. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "A disease-associated frameshift mutation in caveolin-1 disrupts caveolae formation and function through introduction of a de novo ER retention signal." in: Molecular biology of the cell, Vol. 28, Issue 22, pp. 3095-3111, (2018) (PubMed).
: "Characterization of a caveolin-1 mutation associated with both pulmonary arterial hypertension and congenital generalized lipodystrophy." in: Traffic (Copenhagen, Denmark), Vol. 17, Issue 12, pp. 1297-1312, (2017) (PubMed).
: "Clostridium difficile Toxin A Undergoes Clathrin-Independent, PACSIN2-Dependent Endocytosis." in: PLoS pathogens, Vol. 12, Issue 12, pp. e1006070, (2017) (PubMed).
: "Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development." in: Scientific reports, Vol. 6, pp. 20727, (2016) (PubMed).
: "EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF ..." in: The Journal of biological chemistry, Vol. 291, Issue 26, pp. 13465-78, (2016) (PubMed).
: "Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes." in: The Journal of biological chemistry, Vol. 288, Issue 42, pp. 30172-80, (2013) (PubMed).
: "Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis." in: Molecular biology of the cell, Vol. 24, Issue 11, pp. 1776-90, S1-15, (2013) (PubMed).
: "The F-BAR protein PACSIN2 regulates epidermal growth factor receptor internalization." in: The Journal of biological chemistry, Vol. 287, Issue 52, pp. 43438-53, (2012) (PubMed).
: "Pacsin 2 is recruited to caveolae and functions in caveolar biogenesis." in: Journal of cell science, Vol. 124, Issue Pt 16, pp. 2777-85, (2011) (PubMed).
: "The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration." in: Journal of cell science, Vol. 124, Issue Pt 14, pp. 2375-88, (2011) (PubMed).
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: "A disease-associated frameshift mutation in caveolin-1 disrupts caveolae formation and function through introduction of a de novo ER retention signal." in: Molecular biology of the cell, Vol. 28, Issue 22, pp. 3095-3111, (2018) (PubMed).
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- PACSIN2 (Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2))
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别名
- PACSIN2
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背景
- PACSIN may play a role in vesicle formation and transport. This protein homo- and hetero-aggregates with other PACSINs. It also binds dynamin 1, synaptojanin, synapsin 1 and the neural Wiskott-Aldrich syndrome protein (N-WASP). The protein exhibits a cvesicle-like cytoplasmic distribution and is ubiquitously expressed. PACSIN is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). The protein contains 1 FCH domain and 1 SH3 domain.
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分子量
- 55739
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基因ID
- 11252
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NCBI登录号
- NP_001171899, NP_001171900, NP_009160
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UniProt
- Q9UNF0
抗原
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