UHMK1 抗体 (N-Term)
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北京 101111
Quick Overview for UHMK1 抗体 (N-Term) (ABIN392641)
抗原
See all UHMK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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预测反应
- Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This KIST (KIS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KIST (KIS).
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亚型
- Ig Fraction
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anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) (AA 183-385) antibody
UHMK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) (AA 265-295), (C-Term) antibodyUHMK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB5431 unconjugated
anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) antibodyUHMK1 适用: 人, 大鼠, 犬, 猴 WB 宿主: 小鼠 Monoclonal 5E10 unconjugated
anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) antibodyUHMK1 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal 2H4 unconjugated
anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) (AA 331-419) antibodyUHMK1 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) (AA 330-379) antibodyUHMK1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).
: "PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2." in: Investigative ophthalmology & visual science, Vol. 52, Issue 1, pp. 417-26, (2011) (PubMed).
: "Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity." in: Investigational new drugs, Vol. 28, Issue 4, pp. 381-91, (2010) (PubMed).
: "Reduction of Raf kinase inhibitor protein expression by Bcr-Abl contributes to chronic myelogenous leukemia proliferation." in: The Journal of biological chemistry, Vol. 285, Issue 9, pp. 6585-94, (2010) (PubMed).
: "The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia." in: Carcinogenesis, Vol. 31, Issue 11, pp. 2012-21, (2010) (PubMed).
: "FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression." in: The Journal of biological chemistry, Vol. 283, Issue 1, pp. 453-60, (2007) (PubMed).
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: "Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).
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- UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))
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别名
- KIST (KIS)
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背景
- Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
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分子量
- 46546
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基因ID
- 127933
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NCBI登录号
- NP_001171692, NP_653225, NP_787062
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UniProt
- Q8TAS1
抗原
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