PLK3 抗体 (C-Term)
(1 reference)Quick Overview for PLK3 抗体 (C-Term) (ABIN392602)
抗原
See all PLK3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 615-646, C-Term
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预测反应
- Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PLK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 615-646 amino acids from the C-terminal region of human PLK3.
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亚型
- Ig Fraction
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anti-Polo-Like Kinase 3 (PLK3) (AA 487-646) antibody
PLK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polo-Like Kinase 3 (PLK3) (Internal Region) antibodyPLK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polo-Like Kinase 3 (PLK3) antibodyPLK3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polo-Like Kinase 3 (PLK3) (AA 320-333) antibodyVerified PLK3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Polo-Like Kinase 3 (PLK3) (Internal Region) antibodyPLK3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polo-Like Kinase 3 (PLK3) (AA 1-646) antibodyPLK3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polo-Like Kinase 3 (PLK3) (AA 1-646) antibodyPLK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Polo-Like Kinase 3 (PLK3) (AA 385-434) antibodyPLK3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Polo-Like Kinase 3 (PLK3) (Internal Region) antibodyPLK3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 35726-34, (2004) (PubMed).
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: "B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 35726-34, (2004) (PubMed).
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- PLK3 (Polo-Like Kinase 3 (PLK3))
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别名
- PLK3
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背景
- CNK, a member of the CDC5/Polo subfamily of Ser/Thr protein kinases, is involved in regulating M phase functions during the cell cycle. It may also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein. This membrane-associated protein binds to the calcium/integrin-binding protein (CIB). This interaction probably occurs via the POLO-box domain. Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. This protein exhibits a short half-live. In cells of hematopoietic origin, CNK is strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor. Cytokine and cellular adhesion trigger CNK induction. CNK is thought to be phosphorylated as cells enter mitosis and dephosphorylated as cells exit mitosis The protein contains 2 POLO box domains.
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分子量
- 71629
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基因ID
- 1263
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NCBI登录号
- NP_004064
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UniProt
- Q9H4B4
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途径
- Regulation of long-term Neuronal Synaptic Plasticity
抗原
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