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PIK3R3 抗体 (C-Term)

Name: PIK3R3 抗体 (C-Term)
SKU: ABIN392576
Availability: OutOfStock

PIK3R3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB1719 unconjugated

Western blot analysis of lysate from MDA-MB-453 cell line, using PI3KR3 Antibody (ABIN1452207 and ABIN1452209) (ABIN392576 and ABIN2842112). (PIK3R3 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PIK3R3 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PIK3R3 抗体 (C-Term))

IHC (p)

Fluorescent image of cells stained with PIK3R3 Antibody (C-term) A. (PIK3R3 抗体 (C-Term))

3 images

(4 references)

产品编号 ABIN392576

发货至: 中国

Datasheet as PDF

抗原 See all PIK3R3 抗体

PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))
抗原表位
7

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 316-346, C-Term
适用
48

35

18

6

4

3

3

3

3

2

2

2

1

1

1
人
宿主
43

4

1

1
兔
Compatible Secondaries
克隆类型
37

12
多克隆
标记
30

3

2

2

2

2

2

2

1

1

1

1
This PIK3R3 antibody is un-conjugated
应用范围
32

16

14

7

4

2

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This PIK3R3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-346 amino acids from the C-terminal region of human PIK3R3.

克隆位点

RB1719

亚型

Ig Fraction

Top Product

Discover our top product PIK3R3 Primary Antibody
anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (AA 271-380) antibody
PIK3R3 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2F8 unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (AA 1-230), (Regulatory Subunit Gamma) antibody
PIK3R3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (AA 1-461) antibody
PIK3R3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (C-Term) antibody
PIK3R3 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (Center) antibody
PIK3R3 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (AA 1-230), (Regulatory Subunit Gamma) antibody
PIK3R3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) antibody
PIK3R3 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) antibody
PIK3R3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (Center) antibody
PIK3R3 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) antibody
PIK3R3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:100. WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Yang, Cheng, Zhou, Zhu, Hu, Yang: "Overexpression of X-Box Binding Protein 1 (XBP1) Correlates to Poor Prognosis and Up-Regulation of PI3K/mTOR in Human Osteosarcoma." in: International journal of molecular sciences, Vol. 16, Issue 12, pp. 28635-46, (2016) (PubMed).

Wang, Yang, Jin, Deng, Luo, Hu, Wang: "TGF-? regulates the proliferation of lung adenocarcinoma cells by inhibiting PIK3R3 expression." in: Molecular carcinogenesis, (2014) (PubMed).

Eiring, Neviani, Santhanam, Oaks, Chang, Notari, Willis, Gambacorti-Passerini, Volinia, Marcucci, Caligiuri, Leone, Perrotti: "Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis." in: Blood, Vol. 111, Issue 2, pp. 816-28, (2008) (PubMed).

Zhang, Huang, Yang, Greshock, Liang, Hasegawa, Giannakakis, Poulos, OBrien-Jenkins, Katsaros, Butzow, Weber, Coukos: "Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 18 Pt 1, pp. 5314-21, (2007) (PubMed).
抗原

PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))

别名

PIK3R3 (PIK3R3 产品)

别名

AA414954 antibody, p55pik antibody, p55 antibody, p55-GAMMA antibody, pik3r3 antibody, zgc:55564 antibody, zgc:85710 antibody, phosphoinositide-3-kinase regulatory subunit 3 antibody, phosphoinositide-3-kinase, regulatory subunit 3 (gamma) antibody, phosphoinositide-3-kinase, regulatory subunit 3b (gamma) antibody, PIK3R3 antibody, Pik3r3 antibody, pik3r3b antibody

背景

PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The protein is expressed at highest levels in brain and testis. Lower levels are detected in adipose tissue, kidney, heart, lung and skeletal muscle. The protein contains 2 SH2 domains.

分子量

54448

基因ID

8503

NCBI登录号

NP_001107644, NP_003620

UniProt

Q92569