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PIK3R3 抗体 (C-Term)

Name: PIK3R3 抗体 (C-Term)
SKU: ABIN392576
Availability: OutOfStock

This anti-PIK3R3 antibody is a 兔多克隆 antibody detecting PIK3R3 in WB, IF 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 4+ publications.

Western blot analysis of lysate from MDA-MB-453 cell line, using PI3KR3 Antibody (ABIN1452207 and ABIN1452209) (ABIN392576 and ABIN2842112). (PIK3R3 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PIK3R3 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PIK3R3 抗体 (C-Term))

IHC (p)

Fluorescent image of cells stained with PIK3R3 Antibody (C-term) A. (PIK3R3 抗体 (C-Term))

3 images

(4 references)

产品编号 ABIN392576

发货至: 中国

Quick Overview for PIK3R3 抗体 (C-Term) (ABIN392576)

抗原

See all PIK3R3 抗体

PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PIK3R3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1719

Discover our top product PIK3R3 Primary Antibody

抗原表位
7

3

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1

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1
AA 316-346, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This PIK3R3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-346 amino acids from the C-terminal region of human PIK3R3.

亚型

Ig Fraction
anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (AA 271-380) antibody
PIK3R3 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2F8 unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (AA 1-230), (Regulatory Subunit Gamma) antibody
PIK3R3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (AA 1-461) antibody
PIK3R3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (Center) antibody
PIK3R3 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (AA 1-230), (Regulatory Subunit Gamma) antibody
PIK3R3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) antibody
PIK3R3 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) antibody
PIK3R3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (Center) antibody
PIK3R3 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) (AA 201-250) antibody
PIK3R3 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, 斑马鱼, Bat, 猴, Pig, 小鸡, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated

anti-Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) antibody
PIK3R3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated

应用备注

IF: 1:100. WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Yang, Cheng, Zhou, Zhu, Hu, Yang: "Overexpression of X-Box Binding Protein 1 (XBP1) Correlates to Poor Prognosis and Up-Regulation of PI3K/mTOR in Human Osteosarcoma." in: International journal of molecular sciences, Vol. 16, Issue 12, pp. 28635-46, (2016) (PubMed).

Wang, Yang, Jin, Deng, Luo, Hu, Wang: "TGF-? regulates the proliferation of lung adenocarcinoma cells by inhibiting PIK3R3 expression." in: Molecular carcinogenesis, (2014) (PubMed).

Eiring, Neviani, Santhanam, Oaks, Chang, Notari, Willis, Gambacorti-Passerini, Volinia, Marcucci, Caligiuri, Leone, Perrotti: "Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis." in: Blood, Vol. 111, Issue 2, pp. 816-28, (2008) (PubMed).

Zhang, Huang, Yang, Greshock, Liang, Hasegawa, Giannakakis, Poulos, OBrien-Jenkins, Katsaros, Butzow, Weber, Coukos: "Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 18 Pt 1, pp. 5314-21, (2007) (PubMed).
抗原

PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))

别名

PIK3R3

背景

PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The protein is expressed at highest levels in brain and testis. Lower levels are detected in adipose tissue, kidney, heart, lung and skeletal muscle. The protein contains 2 SH2 domains.

分子量

54448

基因ID

8503

NCBI登录号

NP_001107644, NP_003620

UniProt

Q92569