电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PKN beta 抗体 (C-Term)

This anti-PKN beta antibody (ABIN392444) is a Rabbit Polyclonal antibody detecting PKN beta in WB, IHC (p). Suitable for Human.
产品编号 ABIN392444
发货至: 中国

Quick Overview for PKN beta 抗体 (C-Term) (ABIN392444)

抗原

PKN beta

适用

宿主

  • 1

克隆类型

  • 1
多克隆

标记

  • 1
This PKN beta antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1043
  • 抗原表位

    AA 463-492, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PKN beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 463-492 amino acids from the C-terminal region of human PKN beta.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:500. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PKN beta

    背景

    PKN3, a protein kinase C-related molecule, mediates malignant cell growth downstream of activated PI3K. PKN3 is required for invasive prostate cell growth as assessed by 3D cell culture assays and in an orthotopic mouse tumor model by inducible expression of short hairpin RNA (shRNA). PKN3 is regulated by PI3K at both the expression level and the catalytic activity level. Therefore, PKN3 might represent a preferred target for therapeutic intervention in cancers that lack tumor suppressor PTEN function or depend on chronic activation of PI3K.

    分子量

    99421

    基因ID

    29941

    NCBI登录号

    NP_037487

    UniProt

    Q6P5Z2
You are here:
Chat with us!