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PIM2 抗体 (C-Term)

Cited in 1 publication. This 兔 多克隆 anti-PIM2 antibody (Clone RB01288) specifically detects PIM2 in WB, IP 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN392442
发货至: 中国
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Quick Overview for PIM2 抗体 (C-Term) (ABIN392442)

抗原

See all PIM2 抗体
PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))

适用

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宿主

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克隆类型

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多克隆

标记

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This PIM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB01288
  • 抗原表位

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    AA 277-308, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-308 amino acids from the C-terminal region of human PIM2.

    亚型

    Ig Fraction
  • 应用备注

    IP: 1:50~100. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Pogacic, Bullock, Fedorov, Filippakopoulos, Gasser, Biondi, Meyer-Monard, Knapp, Schwaller: "Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity." in: Cancer research, Vol. 67, Issue 14, pp. 6916-24, (2007) (PubMed).

  • 抗原

    PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))

    别名

    PIM2

    背景

    Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli, its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.

    分子量

    34190

    基因ID

    11040

    NCBI登录号

    NP_006866

    UniProt

    Q9P1W9
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