PIM2 抗体 (C-Term)
Quick Overview for PIM2 抗体 (C-Term) (ABIN392442)
抗原
See all PIM2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            抗原表位
- AA 277-308, C-Term
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                                            纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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                                            免疫原
- This PIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-308 amino acids from the C-terminal region of human PIM2.
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                                            亚型
- Ig Fraction
 
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                                            应用备注
- IP: 1:50~100. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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                                            有效期
- 6 months
 
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    - 
                                            : "Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity."    in: Cancer research, Vol. 67, Issue 14, pp. 6916-24, (2007)         (PubMed).        
 
 
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                                            : "Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity."    in: Cancer research, Vol. 67, Issue 14, pp. 6916-24, (2007)         (PubMed).        
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    - PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))
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                                            别名
- PIM2
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                                            背景
- Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli, its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.
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                                            分子量
- 34190
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                                            基因ID
- 11040
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                                            NCBI登录号
- NP_006866
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                                            UniProt
- Q9P1W9
 抗原
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