MST1 抗体 (C-Term)
Quick Overview for MST1 抗体 (C-Term) (ABIN392427)
抗原
See all MST1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 385-415, C-Term
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预测反应
- B
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This MST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the C-terminal region of human MST1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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Individualised proteome profiling of human endometrial tumours improves detection of new prognostic markers." in: British journal of cancer, Vol. 109, Issue 3, pp. 704-13, (2013) (PubMed).
: "Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells." in: Cancer research, Vol. 68, Issue 7, pp. 2266-74, (2008) (PubMed).
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Individualised proteome profiling of human endometrial tumours improves detection of new prognostic markers." in: British journal of cancer, Vol. 109, Issue 3, pp. 704-13, (2013) (PubMed).
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- MST1 (Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1))
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别名
- MST1
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背景
- MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.
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分子量
- 55630
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基因ID
- 6789
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NCBI登录号
- NP_006273
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UniProt
- Q13043
抗原
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