CYP2R1 抗体 (AA 152-180)
Quick Overview for CYP2R1 抗体 (AA 152-180) (ABIN392380)
抗原
See all CYP2R1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 152-180
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This CYP2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CYP2R1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Role of the Drug-Metabolizing Enzyme CYP during Mouse Liver Development." in: Biological & pharmaceutical bulletin, Vol. 39, Issue 12, pp. 2015-2021, (2017) (PubMed).
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: "Role of the Drug-Metabolizing Enzyme CYP during Mouse Liver Development." in: Biological & pharmaceutical bulletin, Vol. 39, Issue 12, pp. 2015-2021, (2017) (PubMed).
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- CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))
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别名
- CYP2R1
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背景
- CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.
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分子量
- 57359
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基因ID
- 120227
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NCBI登录号
- NP_078790
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UniProt
- Q6VVX0
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途径
- Metabolism of Steroid Hormones and Vitamin D
抗原
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