Filamin A 抗体 (AA 1025-1054)
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北京 101111
Quick Overview for Filamin A 抗体 (AA 1025-1054) (ABIN392193)
抗原
See all Filamin A (FLNA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1025-1054
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This FLNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1054 amino acids from human FLNA.
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亚型
- Ig Fraction
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应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Filamin A (FLNA) (Filamin A, alpha (FLNA))
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别名
- FLNA
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背景
- Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.
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分子量
- 280739
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基因ID
- 2316
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NCBI登录号
- NP_001104026, NP_001447
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UniProt
- P21333
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途径
- TCR Signaling, Maintenance of Protein Location
抗原
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