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ANTXR1 抗体 (AA 358-386)

This anti-ANTXR1 antibody is a 兔 多克隆 antibody detecting ANTXR1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN392154
发货至: 中国

Quick Overview for ANTXR1 抗体 (AA 358-386) (ABIN392154)

抗原

See all ANTXR1 抗体
ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ANTXR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB15324
  • 抗原表位

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    AA 358-386

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ANTXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from human ANTXR1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

    别名

    ANTXR1

    背景

    ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.

    分子量

    62789

    基因ID

    84168

    NCBI登录号

    NP_060623, NP_115584, NP_444262

    UniProt

    Q9H6X2
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