TRIB1 抗体 (C-Term)
(3 references)Quick Overview for TRIB1 抗体 (C-Term) (ABIN392118)
抗原
See all TRIB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 341-370, C-Term
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预测反应
- M
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This TRIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human TRIB1.
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亚型
- Ig Fraction
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anti-Tribbles Homolog 1 (TRIB1) (AA 91-191) antibody
TRIB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Tribbles Homolog 1 (TRIB1) (AA 3-91) antibodyTRIB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 1 (TRIB1) (AA 91-191) antibodyTRIB1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tribbles Homolog 1 (TRIB1) (C-Term) antibodyTRIB1 适用: 人, 小鼠, Cow, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 1 (TRIB1) (C-Term) antibodyVerified TRIB1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tribbles Homolog 1 (TRIB1) (Internal Region) antibodyVerified TRIB1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tribbles Homolog 1 (TRIB1) (AA 215-264) antibodyTRIB1 适用: 人, 小鼠, Cow, 大鼠, 马, 豚鼠, 兔, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 1 (TRIB1) (AA 203-372) antibodyTRIB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 1 (TRIB1) antibodyTRIB1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 1 (TRIB1) (C-Term) antibodyTRIB1 适用: 人, 小鼠, Cow, 大鼠, 马, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000. WB: 1:2000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Sin3A-associated protein, 18 kDa, a novel binding partner of TRIB1, regulates MTTP expression." in: Journal of lipid research, Vol. 56, Issue 6, pp. 1145-52, (2015) (PubMed).
: "TRIB1 downregulates hepatic lipogenesis and glycogenesis via multiple molecular interactions." in: Journal of molecular endocrinology, Vol. 52, Issue 2, pp. 145-58, (2014) (PubMed).
: "Identification of tribbles-1 as a novel binding partner of Foxp3 in regulatory T cells." in: The Journal of biological chemistry, Vol. 288, Issue 14, pp. 10051-60, (2013) (PubMed).
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: "Sin3A-associated protein, 18 kDa, a novel binding partner of TRIB1, regulates MTTP expression." in: Journal of lipid research, Vol. 56, Issue 6, pp. 1145-52, (2015) (PubMed).
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- TRIB1 (Tribbles Homolog 1 (TRIB1))
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别名
- TRIB1
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背景
- TRIB1 antibody, also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.
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分子量
- 41009
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基因ID
- 10221
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NCBI登录号
- NP_079471
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UniProt
- Q96RU8
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途径
- Smooth Muscle Cell Migration
抗原
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