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APOE 抗体 (C-Term)

This anti-APOE antibody is a 兔 多克隆 antibody detecting APOE in WB 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN391849
发货至: 中国

Quick Overview for APOE 抗体 (C-Term) (ABIN391849)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

  • 110
  • 85
  • 74
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 123
  • 46
  • 9
  • 2
  • 1

克隆类型

  • 121
  • 59
多克隆

标记

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  • 3
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  • 2
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  • 2
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  • 1
This APOE antibody is un-conjugated

应用范围

  • 145
  • 69
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  • 47
  • 44
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  • 21
  • 13
  • 12
  • 9
  • 6
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  • 2
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  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB15180
  • 抗原表位

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    • 6
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    • 1
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    • 1
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    • 1
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    • 1
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    • 1
    AA 263-292, C-Term

    预测反应

    Pr, Rb

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This APOE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human APOE.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Benga, Krieger, Dimitrova, Zeisel, Parnot, Lupberger, Hildt, Luo, McLauchlan, Baumert, Schuster: "Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 43-53, (2009) (PubMed).

  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    APOE

    背景

    Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

    分子量

    36154

    基因ID

    348

    NCBI登录号

    NP_000032

    UniProt

    P02649

    途径

    Regulation of Cell Size, Lipid Metabolism
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