MAPK15 抗体 (N-Term)
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北京 101111
Quick Overview for MAPK15 抗体 (N-Term) (ABIN391796)
抗原
See all MAPK15 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 32-61, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This MAPK15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human MAPK15.
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亚型
- Ig Fraction
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anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 1-95) antibody
MAPK15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) antibodyMAPK15 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 8C6 unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (pThr175), (pTyr177) antibodyMAPK15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (pThr175), (pTyr177) antibodyMAPK15 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 1-245) antibodyMAPK15 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (pThr175), (pTyr177) antibodyMAPK15 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (Tyr877) antibodyMAPK15 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 1-277) antibodyMAPK15 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 395-444) antibodyMAPK15 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (N-Term) antibodyMAPK15 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "A chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA." in: The Journal of cell biology, Vol. 190, Issue 4, pp. 575-86, (2010) (PubMed).
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: "A chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA." in: The Journal of cell biology, Vol. 190, Issue 4, pp. 575-86, (2010) (PubMed).
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- MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))
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别名
- MAPK15 (ERK8)
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背景
- The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.
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分子量
- 59832
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基因ID
- 225689
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NCBI登录号
- NP_620590
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UniProt
- Q8TD08
抗原
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