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GIPR 抗体 (N-Term)

This anti-GIPR antibody is a 兔 多克隆 antibody detecting GIPR in WB, IHC (p) 和 FACS. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN391714
发货至: 中国

Quick Overview for GIPR 抗体 (N-Term) (ABIN391714)

抗原

See all GIPR 抗体
GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

适用

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  • 31
  • 23
  • 7
  • 4
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  • 2
  • 2
  • 2

宿主

  • 60
  • 3
  • 1

克隆类型

  • 59
  • 3
  • 1
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This GIPR antibody is un-conjugated

应用范围

  • 48
  • 23
  • 14
  • 7
  • 7
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB18125
  • 抗原表位

    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
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    • 1
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    • 1
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    • 1
    • 1
    AA 7-38, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Ugleholdt, Pedersen, Bassi, Füchtbauer, Jørgensen, Kissow, Nytofte, Poulsen, Rosenkilde, Seino, Thams, Holst, Holst: "Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain." in: The Journal of biological chemistry, Vol. 286, Issue 52, pp. 44632-45, (2011) (PubMed).

  • 抗原

    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

    别名

    GIPR

    背景

    GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.

    分子量

    53157

    基因ID

    2696

    NCBI登录号

    NP_000155

    UniProt

    P48546

    途径

    Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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