IDH1 抗体 (AA 116-143)
Our Local Distributor
北京 101111
Quick Overview for IDH1 抗体 (AA 116-143) (ABIN391660)
抗原
See all IDH1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 116-143
-
预测反应
- B, Rat, Sh
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This IDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-143 amino acids from the Central region of human IDH1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:100. IHC-P: 1:50~100. FC: 1:10~50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
- IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
-
别名
- IDH1
-
背景
- IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
-
分子量
- 46659
-
基因ID
- 3417
-
NCBI登录号
- NP_001269315, NP_001269316, NP_005887
-
UniProt
- O75874
-
途径
- Warburg Effect
抗原
-