IMPDH2 抗体 (AA 180-210)
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北京 101111
Quick Overview for IMPDH2 抗体 (AA 180-210) (ABIN391584)
抗原
See all IMPDH2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 180-210
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预测反应
- B, M, Rat, Ha, Zf
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This IMPDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-210 amino acids from the Central region of human IMPDH2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
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别名
- IMPDH2
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背景
- IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. Its gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
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分子量
- 55805
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基因ID
- 3615
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NCBI登录号
- NP_000875
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UniProt
- P12268
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途径
- Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
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