PTTG1 抗体 (N-Term)
(1 reference)Quick Overview for PTTG1 抗体 (N-Term) (ABIN391532)
抗原
See all PTTG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 16-45, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PTTG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human PTTG1.
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亚型
- Ig Fraction
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anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-199) antibody
PTTG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (Internal Region) antibodyVerified PTTG1 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-202) antibodyPTTG1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-202) antibodyPTTG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 93-113) antibodyPTTG1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 101-202) antibodyPTTG1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-202) antibodyPTTG1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-100) antibodyPTTG1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-100) antibodyPTTG1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-100) antibodyPTTG1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2C3 unconjugated
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应用备注
- IF: 1:100. WB: 1:500. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Pituitary tumor transforming gene: a novel therapeutic target for glioma treatment." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 6, pp. 414-21, (2015) (PubMed).
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: "Pituitary tumor transforming gene: a novel therapeutic target for glioma treatment." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 6, pp. 414-21, (2015) (PubMed).
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- PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
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别名
- PTTG1
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背景
- PTTG1 is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The protein has transforming activity in vitro and tumorigenic activity in vivo, and is highly expressed in various tumors. This protein contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the protein can act as a transactivation domain. It is mainly a cytosolic protein, although it partially localizes in the nucleus.
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分子量
- 22024
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基因ID
- 9232
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NCBI登录号
- NP_001269311, NP_001269312, NP_004210
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UniProt
- O95997
抗原
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