Myosin IA 抗体 (AA 276-304)
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Quick Overview for Myosin IA 抗体 (AA 276-304) (ABIN391517)
抗原
See all Myosin IA (MYO1A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 276-304
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This MYO1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human MYO1A.
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亚型
- Ig Fraction
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anti-Myosin IA (MYO1A) (AA 783-1043) antibody
MYO1A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin IA (MYO1A) (AA 781-1043) antibodyMYO1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin IA (MYO1A) (AA 944-1043) antibodyMYO1A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myosin IA (MYO1A) antibodyMYO1A 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Myosin IA (MYO1A)
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别名
- MYO1A
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背景
- MYO1A belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein envelops an actin core bundle that, by comparison, is static in structure.
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分子量
- 118401
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基因ID
- 4640
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NCBI登录号
- NP_001242970, NP_005370
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UniProt
- Q9UBC5
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途径
- Sensory Perception of Sound
抗原
-
